A Rare Case of Hepatic Vanishing Bile Duct Syndrome Occurring after Combination Therapy with Nivolumab and Cabozantinib in a Patient with Renal Carcinoma

Tyrosine kinase inhibitors (TKIs) Ironing Mat and immune checkpoint inhibitors (ICIs) significantly improve the outcomes of patients with advanced clear cell renal cell carcinoma (ccRCC); however, high-grade toxicities can occur, particularly during combination therapy.Herein, we report a patient with advanced metastatic ccRCC, who developed grade

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Comparison of in vitro and computational experiments on the relation of inter-beat interval and duration of repolarization in a specific type of human induced pluripotent stem cell-derived cardiomyocytes.

We compared a published computational model of the action potential of a specific type of human induced pluripotent stem cell -derived cardiomyocytes (hiPSC-CM) Sieve with experimental field potential data with regard to their inter-beat interval and the duration of repolarization.In particular, concomitant changes in inter-beat interval and durati

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